A Genetic Analysis of Crystal Growth

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A Genetic Analysis of Crystal Growth. / Brown, Stanley; Sarikaya, Mehmet; Johnson, E.

In: Journal of Molecular Biology, Vol. 299, No. 3, 2000, p. 725-735.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Brown, S, Sarikaya, M & Johnson, E 2000, 'A Genetic Analysis of Crystal Growth', Journal of Molecular Biology, vol. 299, no. 3, pp. 725-735. https://doi.org/10.1006/jmbi.2000.3682

APA

Brown, S., Sarikaya, M., & Johnson, E. (2000). A Genetic Analysis of Crystal Growth. Journal of Molecular Biology, 299(3), 725-735. https://doi.org/10.1006/jmbi.2000.3682

Vancouver

Brown S, Sarikaya M, Johnson E. A Genetic Analysis of Crystal Growth. Journal of Molecular Biology. 2000;299(3):725-735. https://doi.org/10.1006/jmbi.2000.3682

Author

Brown, Stanley ; Sarikaya, Mehmet ; Johnson, E. / A Genetic Analysis of Crystal Growth. In: Journal of Molecular Biology. 2000 ; Vol. 299, No. 3. pp. 725-735.

Bibtex

@article{9d633f5074c811dbbee902004c4f4f50,
title = "A Genetic Analysis of Crystal Growth",
abstract = "The regulation of crystal morphology by proteins is often observed in biology. It is a central feature in the formation of hard tissues such as bones, teeth and mollusc shells. We have developed a genetic system in the bacterium Escherichia coli to study the protein-mediated control of crystal growth. We have used the crystallization of gold as a model system and found polypeptides that control the morphology of the resulting gold crystals. Analysis of the crystallization process influenced by these polypeptides indicates they act catalytically by an acid mechanism. Our results suggest that the concepts and methods of microbial genetics are general and can be applied to substances not commonly found in biological systems.",
author = "Stanley Brown and Mehmet Sarikaya and E. Johnson",
note = "Keywords: gold; crystal morphology; peptide display",
year = "2000",
doi = "10.1006/jmbi.2000.3682",
language = "English",
volume = "299",
pages = "725--735",
journal = "Journal of Molecular Biology",
issn = "0022-2836",
publisher = "Academic Press",
number = "3",

}

RIS

TY - JOUR

T1 - A Genetic Analysis of Crystal Growth

AU - Brown, Stanley

AU - Sarikaya, Mehmet

AU - Johnson, E.

N1 - Keywords: gold; crystal morphology; peptide display

PY - 2000

Y1 - 2000

N2 - The regulation of crystal morphology by proteins is often observed in biology. It is a central feature in the formation of hard tissues such as bones, teeth and mollusc shells. We have developed a genetic system in the bacterium Escherichia coli to study the protein-mediated control of crystal growth. We have used the crystallization of gold as a model system and found polypeptides that control the morphology of the resulting gold crystals. Analysis of the crystallization process influenced by these polypeptides indicates they act catalytically by an acid mechanism. Our results suggest that the concepts and methods of microbial genetics are general and can be applied to substances not commonly found in biological systems.

AB - The regulation of crystal morphology by proteins is often observed in biology. It is a central feature in the formation of hard tissues such as bones, teeth and mollusc shells. We have developed a genetic system in the bacterium Escherichia coli to study the protein-mediated control of crystal growth. We have used the crystallization of gold as a model system and found polypeptides that control the morphology of the resulting gold crystals. Analysis of the crystallization process influenced by these polypeptides indicates they act catalytically by an acid mechanism. Our results suggest that the concepts and methods of microbial genetics are general and can be applied to substances not commonly found in biological systems.

U2 - 10.1006/jmbi.2000.3682

DO - 10.1006/jmbi.2000.3682

M3 - Journal article

VL - 299

SP - 725

EP - 735

JO - Journal of Molecular Biology

JF - Journal of Molecular Biology

SN - 0022-2836

IS - 3

ER -

ID: 185393