TY - JOUR

T1 - Different dynamics of chiral and racemic (L- and DL-) serine crystals

T2 - Evidenced by incoherent inelastic neutron and Raman scattering

AU - Bordallo, Heloisa N.

AU - Kolesov, Boris A.

AU - Boldyreva, Elena V.

AU - Juranyi, Fanni

PY - 2007/9/12

Y1 - 2007/9/12

N2 - Interest in chiral versus racemic amino acid forms stems from their different solid-state properties associated to the packing arrangement that leads to starkly different physical behavior. Here we focus on the different dynamic properties of the chiral (l-form) and racemic (dl-form) crystals of serine, (C3H7NO3). Measuring incoherent inelastic neutron and Raman scattering over a wide temperature range we could assess a subtle dynamical transition in l-serine near 150 K. The difference in the dynamic properties of the crystals of l- and dl-serine evidenced from our spectroscopic studies is in a good agreement with the different CP(T) dependences and different structuralstrain of the two forms on cooling. Despite a higher bulk density, the molecular fragments in the crystals of l-serine are more dynamic than in dl-serine, and this manifests itself in the incoherent inelastic neutron and Raman spectra, as well as in a higher heat capacity, a higher thermal expansion coefficient, or in the NMR-spectra.

AB - Interest in chiral versus racemic amino acid forms stems from their different solid-state properties associated to the packing arrangement that leads to starkly different physical behavior. Here we focus on the different dynamic properties of the chiral (l-form) and racemic (dl-form) crystals of serine, (C3H7NO3). Measuring incoherent inelastic neutron and Raman scattering over a wide temperature range we could assess a subtle dynamical transition in l-serine near 150 K. The difference in the dynamic properties of the crystals of l- and dl-serine evidenced from our spectroscopic studies is in a good agreement with the different CP(T) dependences and different structuralstrain of the two forms on cooling. Despite a higher bulk density, the molecular fragments in the crystals of l-serine are more dynamic than in dl-serine, and this manifests itself in the incoherent inelastic neutron and Raman spectra, as well as in a higher heat capacity, a higher thermal expansion coefficient, or in the NMR-spectra.

UR - http://www.scopus.com/inward/record.url?scp=34548776471&partnerID=8YFLogxK

U2 - 10.1021/ja073351n

DO - 10.1021/ja073351n

M3 - Journal article

AN - SCOPUS:34548776471

VL - 129

SP - 10984

EP - 10985

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

SN - 0002-7863

IS - 36

ER -