A highly sensitive sensor for carcinoembryonic antigen based on AlGaN/GaN high-electron-mobility transistors

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

A highly sensitive sensor for carcinoembryonic antigen based on AlGaN/GaN high-electron-mobility transistors. / Huang, WeiSun; Hu, Shengjie; Jiang, Xuecheng; Weng, Yuyan; Liu, Yu; Tang, Xue; Yang, Guofeng; Wang, Xun; Lu, Naiyan.

In: Nanotechnology, Vol. 34, No. 31, 315203, 30.07.2023.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Huang, W, Hu, S, Jiang, X, Weng, Y, Liu, Y, Tang, X, Yang, G, Wang, X & Lu, N 2023, 'A highly sensitive sensor for carcinoembryonic antigen based on AlGaN/GaN high-electron-mobility transistors', Nanotechnology, vol. 34, no. 31, 315203. https://doi.org/10.1088/1361-6528/acd1f2

APA

Huang, W., Hu, S., Jiang, X., Weng, Y., Liu, Y., Tang, X., Yang, G., Wang, X., & Lu, N. (2023). A highly sensitive sensor for carcinoembryonic antigen based on AlGaN/GaN high-electron-mobility transistors. Nanotechnology, 34(31), [315203]. https://doi.org/10.1088/1361-6528/acd1f2

Vancouver

Huang W, Hu S, Jiang X, Weng Y, Liu Y, Tang X et al. A highly sensitive sensor for carcinoembryonic antigen based on AlGaN/GaN high-electron-mobility transistors. Nanotechnology. 2023 Jul 30;34(31). 315203. https://doi.org/10.1088/1361-6528/acd1f2

Author

Huang, WeiSun ; Hu, Shengjie ; Jiang, Xuecheng ; Weng, Yuyan ; Liu, Yu ; Tang, Xue ; Yang, Guofeng ; Wang, Xun ; Lu, Naiyan. / A highly sensitive sensor for carcinoembryonic antigen based on AlGaN/GaN high-electron-mobility transistors. In: Nanotechnology. 2023 ; Vol. 34, No. 31.

Bibtex

@article{357094c9213e4ae7a8451f1a9c7b69d4,
title = "A highly sensitive sensor for carcinoembryonic antigen based on AlGaN/GaN high-electron-mobility transistors",
abstract = "Carcinoembryonic antigen (CEA) is a well-known biomarker and validated serum biomarker for lung cancer. We introduce a simple label-free method for CEA detection. Specific recognition of CEA was made possible by immobilizing CEA antibodies in the sensing region of AlGaN/GaN high-electron-mobility transistors. The biosensors have a detection limit of 1 fg ml(-1) in phosphate buffer solution. This approach has advantages of integration, miniaturization, low cost, and rapid detection compared to other testing methods for lung cancer and could be used in future medical diagnostics.",
keywords = "AlGaN, GaN HEMT, biosensor, CEA, lung cancer screening, CANCER STATISTICS, LUNG-CANCER, BIOMARKERS",
author = "WeiSun Huang and Shengjie Hu and Xuecheng Jiang and Yuyan Weng and Yu Liu and Xue Tang and Guofeng Yang and Xun Wang and Naiyan Lu",
year = "2023",
month = jul,
day = "30",
doi = "10.1088/1361-6528/acd1f2",
language = "English",
volume = "34",
journal = "Nanotechnology",
issn = "0957-4484",
publisher = "Institute of Physics Publishing Ltd",
number = "31",

}

RIS

TY - JOUR

T1 - A highly sensitive sensor for carcinoembryonic antigen based on AlGaN/GaN high-electron-mobility transistors

AU - Huang, WeiSun

AU - Hu, Shengjie

AU - Jiang, Xuecheng

AU - Weng, Yuyan

AU - Liu, Yu

AU - Tang, Xue

AU - Yang, Guofeng

AU - Wang, Xun

AU - Lu, Naiyan

PY - 2023/7/30

Y1 - 2023/7/30

N2 - Carcinoembryonic antigen (CEA) is a well-known biomarker and validated serum biomarker for lung cancer. We introduce a simple label-free method for CEA detection. Specific recognition of CEA was made possible by immobilizing CEA antibodies in the sensing region of AlGaN/GaN high-electron-mobility transistors. The biosensors have a detection limit of 1 fg ml(-1) in phosphate buffer solution. This approach has advantages of integration, miniaturization, low cost, and rapid detection compared to other testing methods for lung cancer and could be used in future medical diagnostics.

AB - Carcinoembryonic antigen (CEA) is a well-known biomarker and validated serum biomarker for lung cancer. We introduce a simple label-free method for CEA detection. Specific recognition of CEA was made possible by immobilizing CEA antibodies in the sensing region of AlGaN/GaN high-electron-mobility transistors. The biosensors have a detection limit of 1 fg ml(-1) in phosphate buffer solution. This approach has advantages of integration, miniaturization, low cost, and rapid detection compared to other testing methods for lung cancer and could be used in future medical diagnostics.

KW - AlGaN

KW - GaN HEMT

KW - biosensor

KW - CEA

KW - lung cancer screening

KW - CANCER STATISTICS

KW - LUNG-CANCER

KW - BIOMARKERS

U2 - 10.1088/1361-6528/acd1f2

DO - 10.1088/1361-6528/acd1f2

M3 - Journal article

C2 - 37137294

VL - 34

JO - Nanotechnology

JF - Nanotechnology

SN - 0957-4484

IS - 31

M1 - 315203

ER -

ID: 347790240