We derive a distance of 15.8 0.4 Mpc to the archetypal Seyfert 1 galaxy NGC 4151 based on the near-infrared Cepheid period-luminosity relation and new Hubble Space Telescope multiband imaging. This distance determination, based on measurements of 35 long-period (P> 25 days) Cepheids, will support the absolute calibration of the supermassive black hole mass in this system, as well as studies of the dynamics of the feedback or feeding of its active galactic nucleus.