– Niels Bohr Institute - University of Copenhagen

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Talk by dr. Sedigheh Sajadian, Sharif University, Teheran, Iran

29 August 2016 kl. 14:00

Understanding the EROS2 observations towards the spiral arms within a classical Galactic model framework Read more

Seminar: Yujiro Hayashi

30 August 2016 kl. 14:15

On August 30 at 14:15 in room 305, 3rd floor, building 2 at H.C.Ø. Professor Yujiro Hayashi from Tohoku University, Japan will give a talk about 'Pot Economy and Time Economy in the Synthesis of Biologically Active Molecules'. Read more

Master Thesis Defence by Andreas Nørgård Larsen

30 August 2016 kl. 14:15

Structural analysis of unconventional nanodiscs - based on small-angle X-ray scattering and coarse-grained molecular dynamics simulations.

This thesis is part of a 4-year combined master’s and PhD program, which focuses on the use and development of small-angle X-ray and neutron scattering (SAXS and SANS) on biological macromolecules, in particular nanodiscs and membrane proteins.

In this master thesis I present structural analyses of two different unconventional nanodisc systems. Conventional nanodiscs have two units of the apolipoprotein A1-based membrane scaffolding protein MSP1 wrapped around a lipid bilayer as a protein belt. The ~100 Å nanodiscs can host membrane proteins for structural and functional studies and can function as drug-delivery system for hydrophobic cargo. Unconventional nanodiscs have subsequently been developed with alternative protein constituents, to find systems that are better suited for some membrane proteins or drugs, and to study the nature of these lipoprotein particles.

This master thesis consists of three parts under the common theme of combining small-angle scattering with other sources of information.

The first part is a molecular dynamics (MD) simulation study of three dimer peptide nanodiscs. These nanodiscs have previously been shown to stabilize the 7 transmembrane protein bacteriorhodopsin and the system could be tuned with respect to size and stability of the formed discs by changing the inter-helical linkers. The simulations presented here gave a comprehensive picture of the self-assembly process of the system. Furthermore, the simulations aided the interpretation of the SAXS and SANS data.

The second part is an investigation of high density lipoproteins with full length apolipoprotein E (apoE-FL) and with a truncated version of apoE only consisting of the central domain (apoE-8x22). Both formed nanodiscs, but different from conventional nanodiscs. SAXS data were consistent with a model for apoE-FL with two units of apoE per disc and two helical bundles on the rim of the nanodisc, whereas for apoE-8x22, a model with four proteins per belt was needed to describe data.

The third part investigated a Bayesian approach to analyze SAXS and SANS data, where prior knowledge could be included directly in the analysis by introducing prior probability distributions for the model parameters. The method suggested that a new quantity Q should be minimized instead of χ^2, namely Q= χ^2+αS^2+2ln⁡(α), such that the solution was regularized by the prior distributions S^2, with α weighing prior knowledge and χ^2. Moreover, the Bayesian approach provided a way to compare the probability of refined models using Bayes Factor. Finally, a novel measure for the information content of data was presented and it was argued that this measure was superior to similar measures in frequentist statistics.

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Master defense by Adam Mielke

30 August 2016 kl. 16:00

Exact Zero Modes in Coupled Chiral Systems Read more

QDev Seminar: Roman Luthcyn

31 August 2016 kl. 13:15

Coulomb blockade effect in a proximitized nanowire Read more

Talk by Marc Moniez, CNRS research director at Laboratoire de l’Accélérateur Linéaire, Université de Paris-Sud

31 August 2016 kl. 14:00

LSST: The Large Synoptic Survey Telescope Read more

Master´ s thesis defense by Kyle Honsinger

01 September 2016 kl. 14:00

Human Impacts on interannual and interdecadal variability of atmospheric circulation and surface climate Read more

Talk by Max Berkelhammer

02 September 2016 kl. 14:00

Max Berkelhammer, assistant professor at University of Illnois, Chicago will give a talk on Friday September the 2nd after the status meeting, i.e. 2pm.
The title for the talk will be Carbonyl sulfide: A new proxy for global terrestrial productivity.
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QDev Seminar: Chetan Nayak

02 September 2016 kl. 14:30

Time Crystals

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Master's thesis defense by Kasper Elm Heintz

06 September 2016 kl. 13:15

Tuesday, 6 September @ 13:15. Title: Exploring New Methods of Selecting Quasars Read more

Talk by Professor Bo Reipurth, University of Hawaii

06 September 2016 kl. 14:00

George Herbig and Early Stellar Evolution

 

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Master thesis defence by Mika Lanzky

07 September 2016 kl. 14:00

Ice core data from Renland. Investigation of firn cores, main cores and evaluation of isotope-enabled GCMs for Renland.

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Master's thesis defense by Maren Malling

09 September 2016 kl. 10:00

Friday, 9 September @ 10:00. Title: The Balmer Decrement of Low Redshift Active Galactic Nuclei – Comparing two methods of calculation for a large sample Read more

Ph.D. Deffense: Samuel McEwan Walsh

09 September 2016 kl. 14:00

On September 9 at 14:00 in Aud. 5 at H.C.Ø. Samuel McEwan Walsh will give a public lecture on the thesis entitled 'High content analysis of compositional heterogeneities to study GPCR oligomerization'. Read more

NSC Seminar: Martin Andersson

09 September 2016 kl. 15:00

On September 9 at 15:00, associate professor Martin Andersson wil give a talk at the NSC Seminar.  Read more

NBA History of Science Seminar

12 September 2016 kl. 14:15

Thomas Kaiserfeld, "European Neutrons from Parasitic Research to Global Strategy:  Realizing Plans for a Transnational European Spallation Source in the Wake of the Cold War."

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Talk by Laure Zanna

19 September 2016 kl. 11:00

Prof. Laure Zanna from the University of Oxford will present her work on the workings of the Atlantic Meridional Overturning Circulation.
Title: to be announced.

 
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NBA History of Science Seminar

28 September 2016 kl. 14:15

Roberto Lalli, "Building a Scientific Community in the Post-WWII Era: A Network Analysis of the Renaissance of General Relativity."

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NSC Seminar: Andreas Kjær

07 October 2016 kl. 15:00

On October 7 at 15:00, professor Andreas Kjær will give a talk at the NSC Seminar. Read more

Science Dating 2016

04 November 2016

This years Science Dating will be held at November 4 2016.  Read more

PhD course - Frontiers in particle physics: Flavour physics

07 November 2016

The PhD course aims primarily at theoretical and experimental particle or astro-particle physics PhD students. Read more

NSC Seminar: Jiwoong Lee

25 November 2016 kl. 15:00

On November 25 at 15:00, assistant professor Jiwoong Lee will give a talk at the NSC Seminar.  Read more

Upcoming events

31 December 2016 kl. 09:00

There are currently no upcoming events at the X-Ray and Neutron Science group Read more