Recent high angular resolution (∼ 0\buildrel{\prime\prime}\over{.} 2) ALMA observations of the 1.1 mm continuum and of HCO+ J = 3–2 and HCN J = 3–2 gas toward the binary protostar IRS 43 reveal multiple Keplerian disks that are significantly misaligned (\gt 60^\circ ), both in inclination and position angle and also with respect to the binary orbital plane. Each stellar component has an associated circumstellar disk while the binary is surrounded by a circumbinary disk. Together with archival VLA measurements of the stellar positions over 25 years, and assuming a circular orbit, we use our continuum measurements to determine the binary separation, a=74+/- 4 {au}, and its inclination, i\lt 30^\circ . The misalignment in this system suggests that turbulence has likely played a major role in the formation of IRS 43.