Master Thesis Defense by Frederik Becher – Niels Bohr Institute - University of Copenhagen

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Niels Bohr Institute > Calendar > NBI Calendar 2014 > Master Thesis Defense ...

Master Thesis Defense by Frederik Becher

 

 

Pressure Perturbation Calorimetry

Several experiments have indicated a linear relation between the total enthalpy and volume change in lipid systems. In the current thesis we investigate if this behaviour is valid for the whole temperature range, and therefore for the heat capacity at constant pressure cp and the thermal expansion coefficient αV. The phase transition of lipid membranes was measured using three different calorimetric methods.

Subsequently the heat capacity at constant pressure cp was compared with the thermal expansion coefficient  αV. In addition, the effect of cholesterol and lidocaine was elucidated using different sample concentrations. The results, and their significance, will be discussed according to the theoretical predictions.