Single Molecule Trap and Ice Lithography – Niels Bohr Institute - University of Copenhagen

Niels Bohr Institute > Calendar > 2011 > Single Molecule Trap a...

Single Molecule Trap and Ice Lithography

Trapping, identifying, and manipulating a single biological molecule will bring new knowledge and applications to biology, chemistry, physics and nanosciences. I will present the visions and prospects for a trap by uniting nanopore sensor with integrated nanoelectronics.
Nanopores are single molecule sensors that are able to distinguish single DNA nucleotides, and I will discuss measurement of protein molecules and detection of intermolecular interactions with solid-state nanopores.

I will then present a novel approach to fabricate nanodevices by ice lithography. A focused electron beam selectively removes frozen water, and an ice mask is formed. The ice mask could be used for pattern transfer techniques such as lift-off. Ice lithography might be the key for the realization of the single molecule trap.

Talk by Anpan Han, Dept. Physics, Harvard University